Ruthenium-catalyzed Ionic Hydrogenation Reactions: Mechanistic Studies and Synthetic Applications

Homogeneous hydrogenation of C=N bonds remains achallenge to catalysis, particularly when enantiofaceselectivity is needed. During the past decade someprogress has been made in this area; however, highenantioselectivities has been obtained only forlimited classes of imines or their derivatives. Thereis thus a great need to develop new catalyst systemsfor asymmetric hydrogenation of C=N bonds. This bookbegins with a brief literature survey on themechanisms of C=N hydrogenation, followed by adetailed description of ionic hydrogenation, analternative method and new concept for hydrogenation. The main focus of the book is on the scope andmechanism of ruthenium-catalyzed ionic hydrogenationreactions. This information should be useful toindustrial scientists who are seeking chemoselectiveand stereoselective hydrogenation processes, as wellas to academic researchers who are interested inreaction mechanisms and catalyst design.