An Integrated Video and Telemetric Eeg Recording: Measuring Simultaneously Behavioural and Physiological Parameters to Assess Brain Functions

The combined evaluation of physiology and behaviour allows for a complete and comprehensive pre-clinical assessment of central nervous system (CNS) functions both in physiological and pathological conditions. An integrated video-telemetric electroencephalography (Video-tEEG) system was developed to enable simultaneous assessment of animal behaviour by video tracking technologies, and electroencephalographic analysis by radio-telemetry in freely moving rats. This integrated collection of EEG waveforms and activities of animals provides useful and powerful insights into the correlations between behavioral and electrical brain?s activities in different and important areas of research (e.g., convulsion risk assessment, drug-induced sleep-wakefulness disruption, environmental conditions and animal welfare evaluations), also allowing for a reduction of the number of animals used, improving and refining the data quality by maximizing the amount of information gained from each experimental research.